Obesity Is A Rising Epidemic Throughout The United States...

Obesity is a rising epidemic throughout the United States of America. In many cases, people that are obese tend to develop type 2 diabetes, because the pressure of being obese affects the body’s ability to properly use insulin and control blood sugar levels. In many studies, a hypocaloric, or reduced-calorie, diet is suggested as the main solution to the obesity problem. However, throughout these studies there have been contradictions about the impact of dietary iron on obesity-induced insulin resistance. The objective of this study was to determine if mice liver samples with lower iron levels have an increased sensitivity to insulin resistance. Six liver samples with different iron and fat levels were used from mice with 8 week dietary†¦show more content†¦In previous studies, it has also been seen that overweight or obese individuals are at greater risk of iron deficiency than normal weight individuals. Some studies suggest that possible explanations for this poor d ietary iron intake, is increased iron requirements and/or impaired iron absorption. Nutrient Metabolism and Cardiovascular Diseases (2015), concluded that a calorie reduced diet causes the BMI to decrease however, their data showed that ferritin increases with BMI. The American journal of pathology (2013), demonstrated a model of iron overload syndrome in which an iron enriched diet induces insulin resistance, hyperglycemia and visceral adipose tissue. These contradictions causes us to question if iron plays a role in obesity and obesity related insulin resistance. Turk J Haematol (2014), scientists wanted to assess whether dietary iron overload influenced glucose and lipid metabolism as well as insulin resistance in mice, and found that a more iron enriched diet increases serum and hepatic iron while lowering IRP binding activity. 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